Contents

DDD1 - Descriptive statistics - Distribution of sample types

DDD2 - Descriptive statistics - Distribution of batches

DDD3 - Descriptive statistics - Distribution of sample type by batches

DDD4 - Descriptive statistics - CVs

EEE1 - Maternal, Study Pool, and CHEAR; All features; Pareto; Non-parametric mean only

EEE2 - Maternal, Study Pool, and CHEAR; All features; Pareto; Non-parametric mean and variance

EEE3 - Maternal, Study Pool, and CHEAR; All features; UV; Non-parametric mean only

EEE4 - Maternal, Study Pool, and CHEAR; All features; UV; Non-parametric mean and variance

EEE5 - Maternal, Study Pool, and CHEAR; CV <200%; Pareto; Non-parametric mean only

EEE6 - Maternal, Study Pool, and CHEAR; CV <200%; Pareto; Non-parametric mean and variance

EEE7 - Maternal, Study Pool, and CHEAR; CV <200%; UV; Non-parametric mean only

EEE8 - Maternal, Study Pool, and CHEAR; CV <200%; UV; Non-parametric mean and variance

EEE9 - Maternal, Study Pool, and CHEAR; CV <100%; Pareto; Non-parametric mean only

EEE10 - Maternal, Study Pool, and CHEAR; CV <100%; Pareto; Non-parametric mean and variance

EEE11 - Maternal, Study Pool, and CHEAR; CV <100%; UV; Non-parametric mean only

EEE12 - Maternal, Study Pool, and CHEAR; CV <100%; UV; Non-parametric mean and variance

EEE13 - Maternal, Study Pool, and CHEAR; CV <50%; Pareto; Non-parametric mean only

EEE14 - Maternal, Study Pool, and CHEAR; CV <50%; Pareto; Non-parametric mean and variance

EEE15 - Maternal, Study Pool, and CHEAR; CV <50%; UV; Non-parametric mean only

EEE16 - Maternal, Study Pool, and CHEAR; CV <50%; UV; Non-parametric mean and variance

DDD1 - Descriptive statistics - Distribution of sample types

FALSE 
FALSE      Adult      Blank      CHEAR   Maternal Study Pool       <NA> 
FALSE         20         23         29        263         29          0

DDD2 - Descriptive statistics - Distribution of batches

FALSE 
FALSE   1a   1b    2    3 <NA> 
FALSE   95   32  155   82    0

DDD3 - Descriptive statistics - Distribution of sample type by batches

FALSE             
FALSE               1a  1b   2   3 <NA>
FALSE   Adult        8   0  12   0    0
FALSE   Blank        0   0  15   8    0
FALSE   CHEAR        8   3  12   6    0
FALSE   Maternal    72  25 104  62    0
FALSE   Study Pool   7   4  12   6    0
FALSE   <NA>         0   0   0   0    0

DDD4 - Descriptive statistics - CVs

There are 10259 features.

3982 features have CV < 50%.

7604 features have CV < 100%.

9365 features have CV < 200%.

239 features have CV = NA, due to zero non-zero values.

134 features have CV = NA, due to one non-zero value.

EEE1 - Maternal, Study Pool, and CHEAR; All features; Pareto; Non-parametric mean only

FALSE Found 107 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE2 - Maternal, Study Pool, and CHEAR; All features; Pareto; Non-parametric mean and variance

FALSE Found 107 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE3 - Maternal, Study Pool, and CHEAR; All features; UV; Non-parametric mean only

FALSE Found 107 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE4 - Maternal, Study Pool, and CHEAR; All features; UV; Non-parametric mean and variance

FALSE Found 107 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE5 - Maternal, Study Pool, and CHEAR; CV <200%; Pareto; Non-parametric mean only

FALSE Found 81 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE6 - Maternal, Study Pool, and CHEAR; CV <200%; Pareto; Non-parametric mean and variance

FALSE Found 81 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE7 - Maternal, Study Pool, and CHEAR; CV <200%; UV; Non-parametric mean only

FALSE Found 81 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE8 - Maternal, Study Pool, and CHEAR; CV <200%; UV; Non-parametric mean and variance

FALSE Found 81 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE9 - Maternal, Study Pool, and CHEAR; CV <100%; Pareto; Non-parametric mean only

FALSE Found 33 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE10 - Maternal, Study Pool, and CHEAR; CV <100%; Pareto; Non-parametric mean and variance

FALSE Found 33 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE11 - Maternal, Study Pool, and CHEAR; CV <100%; UV; Non-parametric mean only

FALSE Found 33 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE12 - Maternal, Study Pool, and CHEAR; CV <100%; UV; Non-parametric mean and variance

FALSE Found 33 genes with uniform expression within a single batch (all zeros); these will not be adjusted for batch.

EEE13 - Maternal, Study Pool, and CHEAR; CV <50%; Pareto; Non-parametric mean only

EEE14 - Maternal, Study Pool, and CHEAR; CV <50%; Pareto; Non-parametric mean and variance

EEE15 - Maternal, Study Pool, and CHEAR; CV <50%; UV; Non-parametric mean only

EEE16 - Maternal, Study Pool, and CHEAR; CV <50%; UV; Non-parametric mean and variance